Nursing NCC-NNP : Neonatal Nurse Practitioner Exam

  • Exam Code: NCC-NNP
  • Exam Name: Neonatal Nurse Practitioner Exam
  • Updated: Oct 12, 2026
  • Q & A: 177 Questions and Answers

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Nursing NCC-NNP Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Pharmacology9%- Pharmacokinetics and pharmacodynamics
  • 1. Drug metabolism in neonates
- Common drug therapies
  • 1. Medication administration
- Drugs and breastfeeding
  • 1. Medication safety
Topic 2: Embryology, Physiology, Pathophysiology and Systems Management54%- Genetics
  • 1. Genetic syndromes
- Renal and genitourinary
  • 1. Kidney and urinary conditions
- Gastrointestinal
  • 1. Digestive system disorders
- Musculoskeletal
  • 1. Bone and muscle disorders
- Respiratory
  • 1. Respiratory distress and ventilation
- Integumentary
  • 1. Skin conditions
- Cardiac
  • 1. Congenital and acquired cardiac disorders
- Neurological
  • 1. Neurological disorders
- Metabolic and endocrine
  • 1. Metabolic regulation
- Hematopoietic
  • 1. Blood disorders
- Eyes, ears, nose, mouth and throat
  • 1. Sensory and airway conditions
- Infectious diseases
  • 1. Neonatal infections
Topic 3: General Assessment15%- Maternal history affecting the newborn
  • 1. Prenatal and perinatal factors
  • 2. Risk assessment
- Neonatal assessment
  • 1. Physical examination
  • 2. Gestational age evaluation
- Family integration
  • 1. Family-centered care
  • 2. Parent communication
- Discharge planning and follow-up care
  • 1. Post-discharge monitoring
  • 2. Care transition
Topic 4: General Management19%- Resuscitation and stabilization
  • 1. Emergency neonatal care
- Growth and nutrition
  • 1. Nutritional management
- Fluids and electrolytes
  • 1. Fluid balance management
- Thermoregulation
  • 1. Temperature stabilization
Topic 5: Professional Issues3%- Evidence-based practice
  • 1. Clinical research application
- Legal and ethical principles
  • 1. Professional responsibility
- Quality improvement and patient safety
  • 1. Healthcare quality management

Nursing Neonatal Nurse Practitioner Sample Questions:

Question #1

When a neonate is diagnosed with a terminal disease, the mother cries inconsolably, but the father appears detached and calm. The father's reaction is probably an indication of

  • A. delayed grief
  • B. anticipatory grief
  • C. incongruent grief
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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Question #2

The NP is assessing a newborn and notices faint perioral cyanosis. The first response should be to

  • A. activate the Code Blue protocol for your facility
  • B. start oxygen via a mask
  • C. assess the rest of their body to see if there is any cyanosis present in the extremities or if the infant is exhibiting any retractions or other signs of respiratory distress
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

Question #3

What condition can occur in the newborn as a result of Rh incompatibility?

  • A. Sick sinus syndrome
  • B. Hydrops fetalis
  • C. Sickle cell anemia
Reveal Solution  Discussion  0

Correct Answer: B  🗳️

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Question #4

An infant with ABO incompatibility with the mother develops hyperbilirubinemia after birth. The neonate should be monitored for a few weeks after birth for

  • A. kernicterus
  • B. anemia
  • C. congestive heart failure
Reveal Solution  Discussion  0

Correct Answer: B  🗳️

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Question #5

On examining the neonate, the NP notes 9 cafe au lait spots with a diameter greater than
5 mm and freckles on the axilla and inguinal are
a. The infant should be tested for

  • A. neurofibromatosis type 1
  • B. Addison's disease
  • C. Sturge-Weber syndrome
Reveal Solution  Discussion  0

Correct Answer: A  🗳️

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